**115 Killed in Pakistan Blasts **
A leading human rights group says Pakistan's Shi'ite Muslims are living in a state of siege, after a string of bombings across the country killed 115 people and wounded nearly 250, in one of the nation's deadliest days in years.
Ali Dayan Hasan, the Pakistan director of Human Rights Watch, warned Friday that sectarian violence will likely rise, a day after 82 people were killed in Quetta in suicide bomb blasts in a billiards hall frequented by Shi'ites.
He said more than 400 Shi'ites were killed last year and "if yesterday's attack is any indication, it's just going to get worse."
The outlawed militant Sunni group Lashkar-e-Jhangvi contacted local media to claim responsibility.
Shi'ites make up about 20 percent of Pakistan's mostly Sunni Muslim population of 160 million people.
** Obama, Karzai Meet at White House **
U.S. President Barack Obama and Afghan President Hamid Karzai meet Friday at the White House to discuss the future role of the U.S. in Afghanistan, their first meeting since Mr. Obama's re-election.
The two leaders will hold a joint afternoon news conference.
Current plans call for the U.S. to withdraw nearly all of its nearly 70,000 troops from Afghanistan by the end of 2014.
But that plan hinges on a number of conditions, including whether Afghan forces will be able to take over security at that time. It is also unclear what will be the role of the Americans who stay behind, if any do remain.
On Thursday, Mr. Karzai met with Secretary of State Hillary Clinton.
Earlier, at the Pentagon, Defense Secretary Leon Panetta told Mr. Karzai that the U.S. and Afghanistan have come a long way towards making sure Afghanistan will never again become a safe haven for terrorism.
Mr. Karzai expressed appreciation for the years of support from the U.S. and Afghanistan's other allies.
But while Mr. Karzai has often criticized U.S. actions in Afghanistan, he also has spoken about his desire for some U.S. presence to remain.